The league alignment for schools that have elected to play football in Season C (spring) in 2021.
Alignments are subject to change should teams opt out and/or in.
| South |
| Vista PEAK |
| Denver East |
| Denver South |
| Far Northeast |
| Rangeview |
| Hinkley |
| North |
| Fort Collins |
| Westminster |
| Boulder |
| Mountain Range |
| Northglenn |
| Adams City |
| North |
| Thomas Jefferson |
| Denver North |
| Kennedy |
| George Washington |
| Centaurus |
| Abraham Lincoln |
| South |
| Harrison |
| Falcon |
| Skyview |
| Gateway |
| Aurora Central |
| Sierra |
| East |
| Faith Christian |
| The Classical Academy |
| Kent Denver |
| Sand Creek |
| Littleton |
| Denver West |
| Northfield |
| The Academy |
| West |
| Rifle |
| Basalt |
| Glenwood Springs |
| Aspen |
| Steamboat Springs |
| Coal Ridge |
| Montezuma-Cortez |
| Salida |
| East |
| Flatirons Academy |
| Manual |
| Estes Park |
| Clear Creek |
| Ridge View Academy |
| Sheridan |
| West |
| St. Mary's |
| Buena Vista |
| Ellicott |
| Grand Valley |
| Manitou Springs |
| Roaring Fork |
| 8-man |
| Front Range Christian |
| Justice |
| Plateau Valley |
| John Mall |
| Custer County |
| Hoehne |
| Las Animas |
| Primero |