Maverick Handley, a graduate of Mullen, and Quin Cotton, who graduated from Regis Jesuit, were both selected in the 2019 MLB Draft on Tuesday.
Handley, a 2016 graduate of Mullen, was selected in the sixth round, going No. 168 overall to Baltimore.
He is the first former Colorado high school baseball player selected in the 2019 MLB Draft.
Handley is a junior at Stanford, where he has helped the Cardinal reach the Super Regionals. He is hitting .293 with five home runs and 24 RBIs in 56 games this season as the team's starting catcher. In the regional final against Fresno State on Monday, Handley homered twice.
At Mullen, Handley was named first-team all-state as a senior.
He is the first Mullen alum drafted since 2015, when Sam Haggerty was selected by Cleveland.
Cotton was selected two rounds later, in the eighth, by the Cincinnati Reds at No. 234 overall.
A junior center fielder, he hit .331 with four home runs and 37 RBI this season. He earned all-Western Athletic Conference honor for the second consecutive season after leading his team in hits (83) and doubles (21).